M P Lisanti Selected Research

Caveolin 3

2/2004	Caveolinopathies: mutations in caveolin-3 cause four distinct autosomal dominant muscle diseases.
10/2001	Caveolae and caveolin-3 in muscular dystrophy.
6/2001	Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.
12/2000	Limb-girdle muscular dystrophy (LGMD-1C) mutants of caveolin-3 undergo ubiquitination and proteasomal degradation. Treatment with proteasomal inhibitors blocks the dominant negative effect of LGMD-1C mutanta and rescues wild-type caveolin-3.
8/2000	Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype.
6/2000	Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy.
3/2000	Mutation in the CAV3 gene causes partial caveolin-3 deficiency and hyperCKemia.

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M P Lisanti Research Topics

Disease

10	Neoplasms (Cancer) 01/2020 - 07/2000
6	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 07/2008 - 03/2000
5	Adenocarcinoma 12/2001 - 07/2000
4	Muscular Dystrophies (Muscular Dystrophy) 07/2008 - 06/2000
4	Breast Neoplasms (Breast Cancer) 12/2001 - 10/2000
4	Carcinogenesis 12/2001 - 06/2000
3	Carcinoma (Carcinomatosis) 05/2001 - 07/2000
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 10/2001 - 08/2000
1	Multiple Myeloma 01/2020
1	Anorexia 10/2017
1	Inflammation (Inflammations) 10/2017
1	Hypertension (High Blood Pressure) 02/2010
1	Muscular Diseases (Myopathy) 07/2008
1	1 Rippling muscle disease 02/2004
1	Distal Myopathies (Distal Muscular Dystrophy) 02/2004
1	Neoplasm Metastasis (Metastasis) 12/2001
1	Starvation 08/2001
1	Adenoma (Adenomas) 05/2001
1	Shock 03/2001
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2000
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2000
1	Infections 11/2000
1	Chagas Disease (American Trypanosomiasis) 11/2000
1	Obesity 10/2000
1	Cachexia 10/2000
1	Bacterial Infections (Bacterial Infection) 10/2000
1	Insulin Resistance 10/2000
1	Necrosis 08/2000
1	Retinoblastoma (Glioblastoma, Retinal) 07/2000
1	Muscle Weakness 03/2000
1	Type 1C Limb-Girdle Muscular Dystrophy 03/2000

Drug/Important Bio-Agent (IBA)

9	Caveolin 1IBA 12/2001 - 06/2000
7	Caveolin 3IBA 02/2004 - 03/2000
5	Proteins (Proteins, Gene)FDA Link 12/2001 - 06/2000
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 10/2017
2	LigandsIBA 10/2001 - 05/2001
2	AntibodiesIBA 05/2001 - 12/2000
2	Tyrosine (L-Tyrosine)FDA Link 03/2001 - 10/2000
2	Phosphotransferases (Kinase)IBA 11/2000 - 10/2000
2	Creatine Kinase (Creatine Phosphokinase)IBA 08/2000 - 03/2000
1	Antineoplastic Agents (Antineoplastics)IBA 01/2020
1	ChromatinIBA 01/2020
1	Polycomb-Group ProteinsIBA 01/2020
1	NexusIBA 01/2020
1	CyclinsIBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	erucylphosphocholineIBA 02/2010
1	Nitric Oxide Synthase (NO Synthase)IBA 02/2010
1	Aquaporin 4IBA 07/2008
1	DystrophinIBA 07/2008
1	Sarcoglycans (beta Sarcoglycan)IBA 07/2008
1	Glycoproteins (Glycoprotein)IBA 07/2008
1	GTP Phosphohydrolases (GTPases)IBA 12/2001
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 12/2001
1	Estrogen Receptor alphaIBA 10/2001
1	PPAR gammaIBA 05/2001
1	Formaldehyde (Formol)FDA Link 05/2001
1	ParaffinIBA 05/2001
1	Caveolin 2IBA 05/2001
1	Biological ProductsIBA 05/2001
1	Caspase 3 (Caspase-3)IBA 04/2001
1	Oncogene Proteins (Oncogene Protein)IBA 03/2001
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2001
1	Dexamethasone (Maxidex)FDA LinkGeneric 02/2001
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2000
1	Tamoxifen FDA LinkGeneric 12/2000
1	prolylleucineIBA 12/2000
1	Trastuzumab (Herceptin)FDA Link 12/2000
1	SteroidsIBA 12/2000
1	Estrogen ReceptorsIBA 12/2000
1	Endothelin-1 (Endothelin 1)IBA 11/2000
1	Mitogen-Activated Protein KinasesIBA 11/2000
1	beta CateninIBA 10/2000
1	TCF Transcription FactorsIBA 10/2000
1	Cyclin D1IBA 10/2000
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2000
1	Insulin (Novolin)FDA Link 10/2000
1	Serine (L-Serine)FDA Link 10/2000
1	Insulin Receptor Substrate ProteinsIBA 10/2000
1	HoloenzymesIBA 07/2000
1	Epidermal Growth Factor (EGF)IBA 07/2000
1	CaveolinsIBA 06/2000

Therapy/Procedure

1	Immunotherapy 01/2020
1	Therapeutics 12/2000